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Rat BMP-2 protein

Rat BMP-2 protein

Item no.	ABK-PRP120126-1mg
Manufacturer	Abbkine Scientific
Amount	1mg
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Sequence	Amino acid sequence derived from mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Activity	Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 ug/ml.
Protein length	The recombinant human BMP2 monomer consists of 115 amino acids and has a predicted molecular mass of 13 kDa.
Preparation method	E. coli
Purity	> 95 % as determined by SDS-PAGE
Formulation	Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.
Molecular weight	13 kDa
Usage notes	Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat BMP-2 protein in sterile ddH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Storage instructions	Lyophilized Rat BMP-2 protein product should be stored desiccated below -18C. Upon reconstitution, the protein should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping	The product is shipped at ambient temperature.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Gene ID	650
Alternative	BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2
Accession	P12643

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 10/18/2024

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