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IκB-α Polyclonal Antibody

IκB-α Polyclonal Antibody

Item no.	ABK-ABP51654-30ul
Manufacturer	Abbkine Scientific
Amount	30ul
Category	Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	ELISA, Immunofluorescence, Western Blot, Immunohistochemistry
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Immunogen	Synthesized peptide derived from human IkappaB-alpha around the non-phosphorylation site of Y42
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NF-kappa-B inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. NF-kappa-B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Gene ID	4792
Alternative	NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
Other info	IkappaB-alpha Polyclonal Antibody detects endogenous levels of IkappaB-alpha protein.
Accession	P25963

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 30ul

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Delivery expected until 9/13/2024

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