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TIA1 Polyclonal Antibody

TIA1 Polyclonal Antibody

Item no.	ABK-ABP60680-30ul
Manufacturer	Abbkine Scientific
Amount	30ul
Category	Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	ELISA, Western Blot
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Immunogen	Synthesized peptide derived from part region of human TIA1 protein at amino acid sequence of 201-250
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	The product encoded by TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for TIA1.
Gene ID	7072
Alternative	Nucleolysin TIA-1 isoform p40; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA-1; p40-TIA-1
Other info	The antibody detects endogenous levels of TIA1 protein
Accession	P31483

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 30ul

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Delivery expected until 9/13/2024

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