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BTN3A1/2/3 Polyclonal Antibody

BTN3A1/2/3 Polyclonal Antibody

Item no.	ABK-ABP57930-30ul
Manufacturer	Abbkine Scientific
Amount	30ul
Category	Antibodies Immunohistochemistry ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	ELISA, Immunohistochemistry
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Immunogen	Synthesized peptide derived from part region of human BTN3A1/2/3 protein at amino acid sequence of 41-90
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g. BTN2A1; MIM 613590) and BTN3 (e.g. BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al. 2010 [PubMed 20208008]). BTN3A1 (Butyrophilin Subfamily 3 Member A1) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Butyrophilin (BTN) family interactions. An important paralog of BTN3A1 is BTN3A3.
Gene ID	11119
Alternative	Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
Other info	The antibody detects endogenous levels of BTN3A1/2/3
Accession	O00481/P78410/O00478

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 30ul

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Delivery expected until 10/18/2024

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