Item no. |
ABK-ABP54175-200ul |
Manufacturer |
Abbkine Scientific
|
Amount |
200ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IF, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ESR1, ESR, NR3A1, Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
Available |
|
Accession |
P03372 |
Applications Notes |
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications. |
Background |
ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The estrogen receptor 1 localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Description |
Rabbit Anti-ERa (phospho Ser305) Polyclonal Antibody |
Formulation |
Liquid solution |
Gene ID |
2099 |
Immunogen |
Synthesized peptide derived from human ERa around the phosphorylation site of S305 |
Others |
Phospho-ERa (S305) Polyclonal Antibody detects endogenous levels of ERa protein only when phosphorylated at S305. |
Precautions |
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Storage Buffer |
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Storage Instructions |
Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
Tag |
Estrogen receptor |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.