Comparison

Human 26S Proteasome Regulatory Subunit 7 (PSMC2) ELISA Kit European Partner

Item no. abx382519-96
Manufacturer Abbexa
Amount 96 tests
Category
Type Elisa-Kit
Applications ELISA
Specific against Human (Homo sapiens)
Sensitivity < 0.094 ng/ml
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Available
Manufacturer - Category
ELISA Kits
Description
Human 26S Proteasome Regulatory Subunit 7 (PSMC2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 26S Proteasome Regulatory Subunit 7 (PSMC2) concentrations in tissue homogenates, cell lysates and other biological fluids. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Dry Ice
No
Assay Data
Quantitative
Assay Type
Sandwich
Detection Method
Colorimetric
Gene Symbol
PSMC2
Note
This product is for research use only.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
OMIM
154365
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Target Information
26S Proteasome Regulatory Subunit 7 (PSMC2)
UniProt Entry Name
PRS7_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 96 tests
Available: In stock
available

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