Complement C3 (C3) Antibody (HRP)

Complement C3 (C3) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.

C3

Purified by Protein G.

Complement C3 (C3)