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Leptin (LEP) Antibody

Leptin (LEP) Antibody

Manufacturer	Abbexa
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Obesity Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB, IHC
Amount	50 ul
Host	Rabbit
Item no.	abx004338-50
Targets	LEP
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	LEP
Description	LEP Antibody is a Rabbit Polyclonal antibody against LEP. This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Conjugation	Unconjugated
Purification	Affinity purified.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41159
UniProt Entry Name	LEP_HUMAN
Gene Symbol	LEP
Gene ID	3952
Molecular Weight	Calculated MW: 18 kDa
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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