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APAF1 Antibody

APAF1 Antibody

Manufacturer	Abbexa
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	100 ul
Host	Rabbit
Item no.	abx002100-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Origin	Human
Description	APAF1 Antibody is a Rabbit Polyclonal antibody against APAF1. This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. Image Legend: Fig. 1. Western blot analysis of extracts of HeLa cell line, using APAF1 antibody.
Antigen	APAF1
Conjugation	Unconjugated
Immunogen	A synthetic peptide of human APAF1.
Purification	Affinity purified.
Storage	Aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O14727
Molecular Weight	38 kDa
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Lead Time	Shipped within 5-10 working days.
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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