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PDX1 Antibody

PDX1 Antibody

Manufacturer	Abbexa
Type	Antibody Primary
Specific against	Human, Mouse
Isotype	IgG
Applications	WB
Amount	100 ul
Host	Rabbit
Item no.	abx031492-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Description	PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.
Antigen	PDX1
Conjugation	Unconjugated
Immunogen	Human PDX1.
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O00330
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Lead Time	Shipped within 5-10 working days.
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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