MYC (pS62) Antibody

MYC (pS62) Antibody is a Rabbit Polyclonal antibody against MYC (pS62). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.

MYC

This product is for research use only.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

MYC_HUMAN