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Anthrax Toxin Receptor 1 (ANTXR1) Antibody

Anthrax Toxin Receptor 1 (ANTXR1) Antibody

Manufacturer	Abbexa
Category	Antibodies Immunohistochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human
Isotype	IgG
Applications	IHC
Amount	80 ul
Host	Rabbit
Item no.	abx033658-80
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	ANTXR1
Description	ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Conjugation	Unconjugated
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H6X2
Buffer	PBS containing 0.09% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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