« Back
Home /
TSC2 (pS1420) Antibody

TSC2 (pS1420) Antibody

Item no.	abx032002-80
Manufacturer	Abbexa
Amount	80 ul
Category	Antibodies Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Applications	IF, ICC
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Antigen	TSC2 (pS1420)
Description	Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
Conjugation	Unconjugated
Purification	Purified in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49815
UniProt Entry Name	TSC2_HUMAN
Buffer	PBS containing 0.09% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

abx032002-80-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 80 ul

available

Request delivery time