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MEK1 (pS218 / 222) Antibody

MEK1 (pS218 / 222) Antibody

Item no.	abx031877-400
Manufacturer	Abbexa
Amount	400 ul
Quantity options	400 ul 80 ul
Category	Antibodies Immunohistochemistry Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC, ELISA, DB
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MEK1 (phospho-Ser218/222)
Available
Manufacturers Category	Primary Antibodies
Description	MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Dry Ice	No
Buffer	PBS containing 0.09% sodium azide.
Clonality	Polyclonal
Molecular Weight	Calculated MW: 43.4 kDa
Note	This product is for research use only.
Purification	Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Specificity	Predicted to react with Mouse, Rat, Hamster, Drosophila, Xenopus and C. elegans MAP2K1.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information	MEK1 (pS218/222)
UniProt Entry Name	MP2K1_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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