Lipocalin-2 (LCN2), also known as oncogene 24p3 or NGAL (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.
NGAL/LCN2 (Capture Ab) is a Mouse Monoclonal antibody against Human NGAL/LCN2. For ELISA and LF immunoassays, it is recommended to use abx019240 (this product) or
abx019241 as the capture antibody and
abx019242 as the detection antibody.