Description |
Cytokine that promotes the differentiation and viability of monocytes and macrophages.Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.Ligand for colony-stimulating factor-1 receptor CSF1R.Tissue specificity: Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level).Predominantly expressed in spleen.Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. |