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Adapter Molecule Crk (CRK) Antibody

Adapter Molecule Crk (CRK) Antibody

Item no.	abx015829
Manufacturer	Abbexa
Amount	100 ul
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IF, IHC, ICC, ELISA
Specific against	Human
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CRK
Available
Antigen	CRK
Description	This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins.The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Conjugation	Unconjugated
Purification	Unpurified ascites.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P46108
UniProt Entry Name	CRK_HUMAN
Gene Symbol	CRK
Gene ID	1398
OMIM	164762
Molecular Weight	42 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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