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Periplakin (PPL) Antibody

Periplakin (PPL) Antibody

Manufacturer	Abbexa
Category	Oncology Antibodies By Cell Type Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human
Isotype	IgG
Applications	WB, IF, IHC, ICC
Amount	50 ul
Host	Rabbit
Item no.	abx005273-50
Targets	PPL
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	PPL
Description	PPL Antibody is a Rabbit Polyclonal antibody against PPL. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Conjugation	Unconjugated
Purification	Affinity purified.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O60437
UniProt Entry Name	PEPL_HUMAN
Gene Symbol	PPL
Gene ID	5493
Molecular Weight	Calculated MW: 204 kDa Observed MW: 205 kDa
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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