ArtNr |
21-7098-U100 |
Hersteller |
Tonbo Biosciences
|
Menge |
100 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Applikationen |
Bioassay |
Specific against |
Mouse |
Host |
E.coli |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Macrophage Inflammatory Protein-1beta, CCL4, ACT-2, Exodus-3, LAG1 |
Lieferbar |
|
Cross Reactivity |
Human |
Alternative Name |
Macrophage Inflammatory Protein-1beta, CCL4, ACT-2, Exodus-3, LAG1 |
Description |
CCL4 (MIP-1beta) is a mitogen-inducible monokine and member of the CC chemokine family. It is a secreted protein that plays a role in the acute inflammatory response and is a chemoattractant for monocytes, neutrophils, eosinophils, NK cells, and CD4+ T lymphocytes. MIP-1 beta can signal through CCR5 and, by inducing downregulation of this receptor, can block HIV-1 infection of T cells. |
Amino Acid Sequence |
APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN |
Authenticity |
Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Bioactivity |
Using a concentration range of 5.0-20.0 ng/ml, activity is determined by its ability to chemoattract human blood monocytes. |
Endotoxin Level |
Endotoxin level is <0.1 ng/ug of protein (<1 EU/ug). |
Molecular Mass |
Recombinant Mouse MIP-1 beta consists of 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines, and has a molecular weight of 7.8 kDa. |
Protein Content |
Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Purity |
0, 95 |
Research Areas |
AIDS/HIV, Chemotaxis, Immune System, Inflammation, Neurobiology, Wound Healing |
Reconstitution |
See Certificate of Analysis (COA) for lot specific reconstitution information. |
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