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Recombinant Human IL-34 (Carrier-free)

Recombinant Human IL-34 (Carrier-free)

ArtNr	21-8684-U002
Hersteller	Tonbo Biosciences
Menge	2 ug
Kategorie	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins By Organ Bone Cancer
Typ	Proteins Recombinant
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Description	IL-34 is secreted as a dimeric protein that is expressed in a variety of tissues, but is most abundant in the spleen. It shares the M-CSF Receptor, also known as CSF-1R and CD115, with CSF1 (also called M-CSF). IL-34 stimulates monocyte proliferation, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. It also stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1.
Alternative Names	C16orf77
Amino Acid Sequence	NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity	Measured by its ability to induce secretion of MCP-1 from PBMCs.
Endotoxin Level	Endotoxin level is < 0.1 ng/µ g of protein ( < 1EU/µ g).
Molecular Mass	Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
Protein Content	Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Research Areas	Bone, Skeletal, Cartilage; Cancer; Immune System; Inflammation; Proliferation
Purity	95%
Reconstitution	See Certificate of Analysis (COA) for lot specific reconstitution information.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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21-8684-U002-datasheet.pdf

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Menge: 2 ug

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