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Recombinant Human GM-CSF (Carrier-free) Europäischer Partner

ArtNr 21-8339-U005
Hersteller Tonbo Biosciences
Menge 5 ug
Kategorie
Typ Proteins Recombinant
Specific against Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Description
Human GM-CSF, along with other colony stimulating factors, are key drivers of differentiation and proliferation of hematopoietic precursors. GM-CSF increases leukocyte and reticulocyte counts and also recruits eosinophils, macrophages and neutrophils to sites of inflammation. GM-CSF is secreted by macorphages, mast cells, T cells, NK cells, endothelial cells and fibroblasts. Because of its potent ability to mobilize white blood cells, GM-CSF is used therapeutically to stimulate white blood cell production following chemotherapy.
Amino Acid Sequence
MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Authenticity
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Endotoxin Level
Endotoxin level is < 0.1 ng/µ g of protein ( < 1EU/µ g).
Molecular Mass
Recombinant Human GM-CSF is a 14.6 kDa protein consisting of 128 amino acids.
Protein Content
Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Research Areas
Cancer; Cell Culture; Inflammation; Proliferation; Stem Cells & Differentiation; Wound Healing
Purity
98%
Reconstitution
See Certificate of Analysis (COA) for lot specific reconstitution information.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 ug
Lieferbar: Out of stock
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