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Anti-Park7/DJ-1 antibody

Anti-Park7/DJ-1 antibody

ArtNr	STJ120187-100
Hersteller	St John's Laboratory
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies Glial Cell Markers
Typ	Antibody Monoclonal
Applikationen	WB, IHC
Clon	4H4
Specific against	Human, Mouse, Rat, Bovine
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Anti-Parkinson Disease Protein 7 Homolog antibody</br>Anti-Contraception-Associated Protein 1 antibody</br>Anti-Protein Cap1 antibody</br>Anti-Fertility Protein Sp22 antibody</br>Anti-Maillard Deglycase antibody</br>Anti-Parkinsonism-Associated Deglycase
Similar products	Anti-Parkinson Disease Protein 7 Homolog antibody Anti-Contraception-Associated Protein 1 antibody Anti-Protein Cap1 antibody Anti-Fertility Protein Sp22 antibody Anti-Maillard Deglycase antibody Anti-Parkinsonism-Associated Deglycase
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Clonality	Monoclonal
Conjugation	Unconjugated
Formulation	100 ul in PBS + 10 mM NaN3.
Purification	This antibody was protein g purified culture from supernatant.
Uniprot ID	O88767
Storage	Store at-20° C, and avoid repeated freeze-thaw cycles.
Description	Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
Gene ID	117287
Immunogen	Full length recombinant human Park7 expressed in and purification from E. coli.
Tissue specificity	Ubiquitous. Detected on epididymal sperm. Highly expressed in testis and prostate. Detected at lower levels in heart, lung, brain, liver, kidney, seminal vesicle, caput and corpus epididymis.
Cellular localization	Cell Membrane Lipid-Anchor Cytoplasm Membrane Raft Nucleus Mitochondrion Endoplasmic Reticulum Under Normal Conditions Located Predominantly In The Cytoplasm And To A Lesser Extent In The Nucleus And Mitochondrion Translocates To The Mitochondrion And Subsequently To The Nucleus In Response To Oxidative Stress And Exerts An Increased Cytoprotective Effect Against Oxidative Damage Membrane Raft Localization In Astrocytes And Neuronal Cells Requires Palmitoylation
Molecular weight	21 kDa
Dilution range	WB 1:2000; IF 1:500
Alternative names	Anti-Parkinson Disease Protein 7 Homolog antibody Anti-Contraception-Associated Protein 1 antibody Anti-Protein Cap1 antibody Anti-Fertility Protein Sp22 antibody Anti-Maillard Deglycase antibody Anti-Parkinsonism-Associated Deglycase antibody Anti-Protein Dj-1 antibody Anti-Dj-1 antibody Anti-Protein/Nucleic Acid Deglycase Dj-1 antibody Anti-Park7 Cap1 antibody
Protein name	Parkinson Disease Protein 7 Homolog Contraception-Associated Protein 1 Protein Cap1 Fertility Protein Sp22 Maillard Deglycase Parkinsonism-Associated Deglycase Protein Dj-1 Dj-1 Protein/Nucleic Acid Deglycase Dj-1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PARK7_RAT

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Menge: 100 ul

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Lieferung vsl. bis 06.09.2024

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