Anti-NEFM/NF-M antibody

Polyclonal

Total IgY fraction in PBS + 10 mM NaN3.

P12839

Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (Harris et al., 1991). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (Hu et al., 2002).

Preparation containing the extreme C-terminus expressed in and purification from E. Coli.

Expressed in the dorsal root ganglion neurons (at protein level).

145 kDa

Anti-Neurofilament Medium Polypeptide antibody
Anti-Nf-M antibody
Anti-160 Kda Neurofilament Protein antibody
Anti-Neurofilament 3 antibody
Anti-Neurofilament Triplet M Protein antibody
Anti-Nefm Nef3 Nfm antibody

FOR RESEARCH USE ONLY (RUO).