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Anti-CLSTN1 antibody (29-350) (STJ117600) Europäischer Partner

ArtNr STJ117600-50
Hersteller St John's Laboratory
Menge 50 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Mouse, Rat
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Calsyntenin-1 antibody</br>Anti-Alcadein-Alpha antibody</br>Anti-Alc-Alpha antibody</br>Anti-Alzheimer-Related Cadherin-Like Protein antibody</br>Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody</br>Anti-Salc-Alpha-Ctf1-A
Similar products Anti-Calsyntenin-1 antibody
Anti-Alcadein-Alpha antibody
Anti-Alc-Alpha antibody
Anti-Alzheimer-Related Cadherin-Like Protein antibody
Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody
Anti-Salc-Alpha-Ctf1-A
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
O94985
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-350 of human CLSTN1 (NP_055759. 3).
Short Description
Rabbit polyclonal against CLSTN1
Tissue specificity
Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta. Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level).
Cellular localization
Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus Membrane
Cell Projection
Neuron Projection
Cell Junction
Synapse
Postsynaptic Cell Membrane
Nucleus
Neurite Tips
Localized In The Postsynaptic Membrane Of Both Excitatory And Inhibitory Synapses
The Alcicd Fragment Is Translocated To The Nucleus Upon Interaction With Apbb1
Molecular weight
Calculated: 108kDa/109kDa. Observed: 110kDa
Dilution range
WB 1:200-1:2000
Alternative names
Anti-Calsyntenin-1 antibody
Anti-Alcadein-Alpha antibody
Anti-Alc-Alpha antibody
Anti-Alzheimer-Related Cadherin-Like Protein antibody
Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody
Anti-Salc-Alpha-Ctf1-Alpha antibody
Anti-C-Terminal Fragment 1-Alpha antibody
Anti-CLSTN1 CS1 KIAA0911 antibody
Protein name
Calsyntenin-1
Alcadein-Alpha
Alc-Alpha
Alzheimer-Related Cadherin-Like Protein
Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha
Salc-Alpha-Ctf1-Alpha
C-Terminal Fragment 1-Alpha
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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