ArtNr |
STJ115932-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Hla Class Ii Histocompatibility Antigen-Dp Beta 1 Chain antibody</br>Anti-Hla Class Ii Histocompatibility Antigen-Dp(W4 Beta Chain antibody</br>Anti-Mhc Class Ii Antigen Dpb1 antibody</br>Anti-HLA-DPB1 HLA-DP1B antibody |
Similar products |
Anti-Hla Class Ii Histocompatibility Antigen-Dp Beta 1 Chain antibodyAnti-Hla Class Ii Histocompatibility Antigen-Dp(W4 Beta Chain antibodyAnti-Mhc Class Ii Antigen Dpb1 antibodyAnti-HLA-DPB1 HLA-DP1B antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P04440 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human HLA-DPB1 (NP_002112. 3). |
Short Description |
Rabbit polyclonal against HLA-DPB1 |
Cellular localization |
Cell MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum MembraneGolgi ApparatusTrans-Golgi Network MembraneEndosome MembraneLysosome MembraneThe Mhc Class Ii Complex Transits Through A Number Of Intracellular Compartments In The Endocytic Pathway Until It Reaches The Cell Membrane For Antigen Presentation |
Molecular weight |
Calculated: 29kDa. Observed: 29kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Hla Class Ii Histocompatibility Antigen-Dp Beta 1 Chain antibodyAnti-Hla Class Ii Histocompatibility Antigen-Dp(W4 Beta Chain antibodyAnti-Mhc Class Ii Antigen Dpb1 antibodyAnti-HLA-DPB1 HLA-DP1B antibody |
Protein name |
Hla Class Ii Histocompatibility Antigen-Dp Beta 1 ChainHla Class Ii Histocompatibility Antigen-Dp(W4 Beta ChainMhc Class Ii Antigen Dpb1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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