Anti-HLA-DPB1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P04440

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

HLA-DPB1

Rabbit polyclonal against HLA-DPB1

Calculated: 29kDa. Observed: 29kDa

Anti-Hla Class Ii Histocompatibility Antigen-Dp Beta 1 Chain antibody
Anti-Hla Class Ii Histocompatibility Antigen-Dp(W4 Beta Chain antibody
Anti-Mhc Class Ii Antigen Dpb1 antibody
Anti-HLA-DPB1 HLA-DP1B antibody

FOR RESEARCH USE ONLY (RUO).