ArtNr |
STJ114768-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Lactotransferrin antibody</br>Anti-Lactoferrin antibody</br>Anti-Growth-Inhibiting Protein 12 antibody</br>Anti-Talalactoferrin Cleaved Into-Lactoferricin-H antibody</br>Anti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C antibody |
Similar products |
Anti-Lactotransferrin antibodyAnti-Lactoferrin antibodyAnti-Growth-Inhibiting Protein 12 antibodyAnti-Talalactoferrin Cleaved Into-Lactoferricin-H antibodyAnti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P02788 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 500-710 of human LTF (NP_002334. 2). |
Short Description |
Rabbit polyclonal against LTF |
Tissue specificity |
High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine. In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels. Detected in peripheral blood neutrophils (at protein level). Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver. Isoform 1 is expressed in brain, testis and peripheral blood leukocytes.isoform DeltaLf is barely detectable in these tissues. Isoform DeltaLf is expressed in placenta, liver and ovary.isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex. |
Cellular localization |
Isoform 1: SecretedCytoplasmic GranuleSecreted Into Most Exocrine Fluids By Various Endothelial CellsStored In The Secondary Granules Of NeutrophilsIsoform Deltalf: CytoplasmNucleusMainly Localized In The Cytoplasm |
Molecular weight |
Calculated: 73kDa/78kDa. Observed: 78kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Lactotransferrin antibodyAnti-Lactoferrin antibodyAnti-Growth-Inhibiting Protein 12 antibodyAnti-Talalactoferrin Cleaved Into-Lactoferricin-H antibodyAnti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C antibodyAnti-LTF GIG12 LF antibody |
Protein name |
LactotransferrinLactoferrinGrowth-Inhibiting Protein 12Talalactoferrin Cleaved Into-Lactoferricin-HLfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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