Anti-UPK1A antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O00322

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene.

UPK1A

Rabbit polyclonal against UPK1A

Membrane
Multi-Pass Membrane Protein

WB 1:500-1:2000

Uroplakin-1a
Up1a
Tetraspanin-21
Tspan-21
Uroplakin Ia
Upia
Upka

UPK1A_HUMAN