Anti-WIPI1 antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

Rabbit polyclonal to WIPI1.

WIPI1

Rabbit polyclonal against WIPI1

Golgi apparatus, trans-Golgi network. Endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Preautophagosomal structure membrane. Peripheral membrane protein. Cytoplasm, cytoskeleton. Trans elements of the Golgi and peripheral endosomes. Dynamically cycles through these compartments and is susceptible to conditions that modulate membrane flux. Enriched in clathrin-coated vesicles. Upon starvation-induced autophagy, accumulates at subcellular structures in the cytoplasm: enlarged vesicular and lasso-like structures, and large cup-shaped structures predominantly around the nucleus. Recruitment to autophagic membranes is controlled by MTMR14. Labile microtubules specifically recruit markers of autophagosome formation like WIPI1, whereas mature autophagosomes may bind to stable microtubules.

WD repeat domain phosphoinositide-interacting protein 1
WIPI-1
Atg18 protein homolog
WD40 repeat protein interacting with phosphoinositides of 49 kDa
WIPI 49 kDa

FOR RESEARCH USE ONLY (RUO).