ArtNr |
STJ97062-200 |
Hersteller |
St John's Laboratory
|
Menge |
200ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
IF, ELISA, IHC-P |
Clon |
Q100 |
Specific against |
Human |
Host |
Mouse |
Isotype |
IgG1 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Anti-Lactotransferrin antibody</br>Anti-Lactoferrin antibody</br>Anti-Growth-Inhibiting Protein 12 antibody</br>Anti-Talalactoferrin [Cleaved Into-Lactoferricin-H antibody</br>Anti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C] antibo |
Similar products |
Anti-Lactotransferrin antibodyAnti-Lactoferrin antibodyAnti-Growth-Inhibiting Protein 12 antibodyAnti-Talalactoferrin [Cleaved Into-Lactoferricin-H antibodyAnti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C] antibo |
Lieferbar |
|
Clonality |
Monoclonal |
Conjugation |
Unconjugated |
Formulation |
PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol. |
Purification |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Uniprot ID |
P02788 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Description |
Lactoferrin is a protein encoded by the LTF gene which is approximately 78, 1 kDa. Lactoferrin is localised to the cytoplasm and nucleus. It is involved in the innate immune system and the HIV life cycle. This protein falls under the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. It is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. Lactoferrin is expressed in the blood, bone marrow, lung, eye and liver. Mutations in the LTF gene may result in dry eye syndrome. STJ97062 was developed from clone Q100 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Lactoferrin protein. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthetic Peptide |
Short Description |
Mouse monoclonal against Lactoferrin |
Tissue specificity |
High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine. In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels. Detected in peripheral blood neutrophils (at protein level). Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver. Isoform 1 is expressed in brain, testis and peripheral blood leukocytes; isoform DeltaLf is barely detectable in these tissues. Isoform DeltaLf is expressed in placenta, liver and ovary; isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex. |
Cellular localization |
Isoform 1: SecretedCytoplasmic GranuleSecreted Into Most Exocrine Fluids By Various Endothelial CellsStored In The Secondary Granules Of NeutrophilsIsoform Deltalf: CytoplasmNucleusMainly Localized In The Cytoplasm |
Dilution range |
IF 1:50-200ELISA 1:5000-10000IHC 1:50-300 |
Alternative names |
Anti-Lactotransferrin antibodyAnti-Lactoferrin antibodyAnti-Growth-Inhibiting Protein 12 antibodyAnti-Talalactoferrin [Cleaved Into-Lactoferricin-H antibodyAnti-Lfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C] antibodyAnti-LTF GIG12 LF antibody |
Protein name |
LactotransferrinLactoferrinGrowth-Inhibiting Protein 12Talalactoferrin [Cleaved Into-Lactoferricin-HLfcin-H-Kaliocin-1-Lactoferroxin-A-Lactoferroxin-B-Lactoferroxin-C] |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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