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Anti-GHR Antibody Europäischer Partner

ArtNr STJ23783-50
Hersteller St John's Laboratory
Menge 50 ul
Kategorie
Typ Antibody
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GHR antibody, Growth hormone receptor antibody, GH receptor antibody, Somatotropin receptor antibody, GHR antibody
Lieferbar
Storage Conditions
Store at -20C. Avoid freeze / thaw cycles.
Molecular Weight
71.5 kDa
Description
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Immunogen
A synthetic peptide of human GHR
Tissue specificity
Expressed in various tissues with high expression in liver and skeletal muscle, Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem, Isoform 1 expression in placenta is predominant in chorion and decidua, Isoform 4 is highly expressed in placental villi, Isoform 2 is expressed in lung, stomach and muscle, Low levels in liver
Clonality
Polyclonal
Gene symbol
GHR
Dilution range
WB1:500 - 1:2000
Note
For Research Use Only (RUO).
Short Description
Rabbit polyclonal to GHR

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: Out of stock
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