Anti-OPRM1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P35372

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503. 2:c. 118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.

OPRM1

Rabbit polyclonal against OPRM1

Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Axon
Perikaryon
Dendrite
Endosome
Is Rapidly Internalized After Agonist Binding
Isoform 12: Cytoplasm

WB 1:500-1:2000

Mu-Type Opioid Receptor
M-Or-1
Mor-1
Mu Opiate Receptor
Mu Opioid Receptor
Mop
Hmop

OPRM_HUMAN