ArtNr |
STJ115386-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Angiopoietin-Related Protein 4 antibody</br>Anti-Angiopoietin-Like Protein 4 antibody</br>Anti-Hepatic Fibrinogen/Angiopoietin-Related Protein antibody</br>Anti-Hfarp Cleaved Into-Angptl4 N-Terminal Chain-Angptl4 C-Terminal Chain antibody</br>Anti-AN |
Similar products |
Anti-Angiopoietin-Related Protein 4 antibodyAnti-Angiopoietin-Like Protein 4 antibodyAnti-Hepatic Fibrinogen/Angiopoietin-Related Protein antibodyAnti-Hfarp Cleaved Into-Angptl4 N-Terminal Chain-Angptl4 C-Terminal Chain antibodyAnti-AN |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9BY76 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-406 of human ANGPTL4 (NP_647475. 1). |
Short Description |
Rabbit polyclonal against ANGPTL4 |
Tissue specificity |
Detected in blood plasma (at protein level). Detected in liver. Detected in white fat tissue and placenta. Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney. |
Cellular localization |
SecretedExtracellular SpaceExtracellular MatrixThe Unprocessed Form Interacts With The Extracellular MatrixThis May Constitute A Dynamic ReservoirA Regulatory Mechanism Of The Bioavailability Of Angptl4 (Probable) |
Molecular weight |
Calculated: 26kDa/40kDa/45kDa. Observed: |
Dilution range |
IF 1:50-1:200 |
Alternative names |
Anti-Angiopoietin-Related Protein 4 antibodyAnti-Angiopoietin-Like Protein 4 antibodyAnti-Hepatic Fibrinogen/Angiopoietin-Related Protein antibodyAnti-Hfarp Cleaved Into-Angptl4 N-Terminal Chain-Angptl4 C-Terminal Chain antibodyAnti-ANGPTL4 ARP4 HFARP PGAR PP1158 PSEC0166 UNQ171/PRO197 antibody |
Protein name |
Angiopoietin-Related Protein 4Angiopoietin-Like Protein 4Hepatic Fibrinogen/Angiopoietin-Related ProteinHfarp Cleaved Into-Angptl4 N-Terminal Chain-Angptl4 C-Terminal Chain |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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