Anti-LILRB1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q8NHL6

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

LILRB1

Rabbit polyclonal against LILRB1

Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 5: Secreted

WB 1:500-1:2000

Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1
Lir-1
Leukocyte Immunoglobulin-Like Receptor 1
Cd85 Antigen-Like Family Member J
Immunoglobulin-Like Transcript 2
Ilt-2
Monocyte/Macrophage Immunoglobulin-Like Receptor 7
Mir-7
Cd Antigen Cd85j

LIRB1_HUMAN