Anti-WWOX antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q9NZC7

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

WWOX

Rabbit polyclonal against WWOX

Cytoplasm
Nucleus
Mitochondrion
Golgi Apparatus
Partially Localizes To The Mitochondria
Translocates To The Nucleus Upon Genotoxic Stress Or Tnf Stimulation
Translocates To The Nucleus In Response To Tgfb1
Isoform 5 And Isoform 6 May Localize In The Nucleus

WB 1:1000-1:2000

Ww Domain-Containing Oxidoreductase
Fragile Site Fra16d Oxidoreductase
Short Chain Dehydrogenase/Reductase Family 41c Member 1

WWOX_HUMAN