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Anti-NUDT15 antibody

Anti-NUDT15 antibody

ArtNr	STJ110666-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibody</br>Anti-Mutt Homolog 2 antibody</br>Anti-Mth2 antibody</br>Anti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibody</br>Anti-Nudix Motif 15 antibody</br>Anti-Nucleoside Diphosphate-Linked To
Similar products	Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibody Anti-Mutt Homolog 2 antibody Anti-Mth2 antibody Anti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibody Anti-Nudix Motif 15 antibody Anti-Nucleoside Diphosphate-Linked To
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9NV35
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Gene ID	55270
Gene symbol	NUDT15
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753. 1).
Short Description	Rabbit polyclonal against NUDT15
Molecular weight	Calculated: 18kDa. Observed: 19kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:100
Alternative names	Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibody Anti-Mutt Homolog 2 antibody Anti-Mth2 antibody Anti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibody Anti-Nudix Motif 15 antibody Anti-Nucleoside Diphosphate-Linked To Another Moiety X Hydrolase 15 antibody Anti-Nudix Hydrolase 15 antibody Anti-NUDT15 MTH2 antibody
Protein name	Nucleotide Triphosphate Diphosphatase Nudt15 Mutt Homolog 2 Mth2 Nucleoside Diphosphate-Linked Moiety X Motif 15 Nudix Motif 15 Nucleoside Diphosphate-Linked To Another Moiety X Hydrolase 15 Nudix Hydrolase 15
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	NUD15_HUMAN

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Menge: 50ul

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