ArtNr |
STJ110666-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibody</br>Anti-Mutt Homolog 2 antibody</br>Anti-Mth2 antibody</br>Anti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibody</br>Anti-Nudix Motif 15 antibody</br>Anti-Nucleoside Diphosphate-Linked To |
Similar products |
Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibodyAnti-Mutt Homolog 2 antibodyAnti-Mth2 antibodyAnti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibodyAnti-Nudix Motif 15 antibodyAnti-Nucleoside Diphosphate-Linked To |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9NV35 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753. 1). |
Short Description |
Rabbit polyclonal against NUDT15 |
Molecular weight |
Calculated: 18kDa. Observed: 19kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:100 |
Alternative names |
Anti-Nucleotide Triphosphate Diphosphatase Nudt15 antibodyAnti-Mutt Homolog 2 antibodyAnti-Mth2 antibodyAnti-Nucleoside Diphosphate-Linked Moiety X Motif 15 antibodyAnti-Nudix Motif 15 antibodyAnti-Nucleoside Diphosphate-Linked To Another Moiety X Hydrolase 15 antibodyAnti-Nudix Hydrolase 15 antibodyAnti-NUDT15 MTH2 antibody |
Protein name |
Nucleotide Triphosphate Diphosphatase Nudt15Mutt Homolog 2Mth2Nucleoside Diphosphate-Linked Moiety X Motif 15Nudix Motif 15Nucleoside Diphosphate-Linked To Another Moiety X Hydrolase 15Nudix Hydrolase 15 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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