ArtNr |
STJ29200-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Butyrophilin-Like Protein 2 antibody</br>Anti-Btl-Ii antibody</br>Anti-BTNL2 antibody |
Similar products |
Anti-Butyrophilin-Like Protein 2 antibodyAnti-Btl-Ii antibodyAnti-BTNL2 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9UIR0 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548. 1). |
Short Description |
Rabbit polyclonal against BTNL2 |
Tissue specificity |
Expressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus. |
Cellular localization |
MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2 Is Present In The NuclearVesicle And Plasma MembranesIsoform 3 Is Found In Cytoplasmic Vesicle Structures And Is Not Membrane Bound |
Molecular weight |
Calculated: 19kDa/27kDa/28kDa/30kDa/43kDa/50kDa. Observed: 60kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Butyrophilin-Like Protein 2 antibodyAnti-Btl-Ii antibodyAnti-BTNL2 antibody |
Protein name |
Butyrophilin-Like Protein 2Btl-Ii |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.