Anti-SECISBP2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q96T21

The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.

SECISBP2

Rabbit polyclonal against SECISBP2

Isoform 1: Nucleus
Isoform 2: Mitochondrion

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Selenocysteine Insertion Sequence-Binding Protein 2
Secis-Binding Protein 2

SEBP2_HUMAN