Anti-PIAS2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O75928

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

PIAS2

Rabbit polyclonal against PIAS2

Nucleus Speckle
Nucleus
Pml Body
Colocalizes At Least Partially With Promyelocytic Leukemia Nuclear Bodies (Pml Nbs)
Colocalizes With Sumo1 In Nuclear Granules

WB 1:500-1:2000

E3 Sumo-Protein Ligase Pias2
Androgen Receptor-Interacting Protein 3
Arip3
Dab2-Interacting Protein
Dip
E3 Sumo-Protein Transferase Pias2
Msx-Interacting Zinc Finger Protein
Miz1
Pias-Ny Protein
Protein Inhibitor Of Activated Stat X
Protein Inhibitor Of Activated Stat2

PIAS2_HUMAN