ArtNr |
STJ27303-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibody</br>Anti-Imp Dehydrogenase 2 antibody</br>Anti-Impd 2 antibody</br>Anti-Impdh 2 antibody</br>Anti-Impdh-Ii antibody</br>Anti-IMPDH2 IMPD2 antibody |
Similar products |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibodyAnti-Imp Dehydrogenase 2 antibodyAnti-Impd 2 antibodyAnti-Impdh 2 antibodyAnti-Impdh-Ii antibodyAnti-IMPDH2 IMPD2 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P12268 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy-and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human IMPDH2 (NP_000875. 2). |
Short Description |
Rabbit polyclonal against IMPDH2 |
Tissue specificity |
IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
Cellular localization |
CytoplasmNucleus |
Molecular weight |
Calculated: 55kDa. Observed: 56kDa |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibodyAnti-Imp Dehydrogenase 2 antibodyAnti-Impd 2 antibodyAnti-Impdh 2 antibodyAnti-Impdh-Ii antibodyAnti-IMPDH2 IMPD2 antibody |
Protein name |
Inosine-5'-Monophosphate Dehydrogenase 2Imp Dehydrogenase 2Impd 2Impdh 2Impdh-Ii |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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