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Anti-PARD6A antibody

Anti-PARD6A antibody

ArtNr	STJ24893-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Partitioning Defective 6 Homolog Alpha antibody</br>Anti-Par-6 antibody</br>Anti-Par-6 Alpha antibody</br>Anti-Par-6a antibody</br>Anti-Par6c antibody</br>Anti-Tax Interaction Protein 40 antibody</br>Anti-Tip-40 antibody</br>Anti-PARD6A PAR6A antibod
Similar products	Anti-Partitioning Defective 6 Homolog Alpha antibody Anti-Par-6 antibody Anti-Par-6 Alpha antibody Anti-Par-6a antibody Anti-Par6c antibody Anti-Tax Interaction Protein 40 antibody Anti-Tip-40 antibody Anti-PARD6A PAR6A antibod
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9NPB6
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID	50855
Gene symbol	PARD6A
Immunogen	A synthetic peptide of human PARD6A
Short Description	Rabbit polyclonal against PARD6A
Tissue specificity	Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
Cellular localization	Cytoplasm Cell Membrane Cell Projection Ruffle Cell Junction Tight Junction Cytoskeleton Microtubule Organizing Center Centrosome Centriolar Satellite Colocalizes With Gtp-Bound Cdc42 Or Rac1 At Membrane Ruffles And With Pard3 And Prkci At Epithelial Tight Junctions Recruited To The Centrosome By A Microtubule And Dynein-Dynactin-Dependent Mechanism
Molecular weight	Calculated: 37kDa. Observed: 47kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Partitioning Defective 6 Homolog Alpha antibody Anti-Par-6 antibody Anti-Par-6 Alpha antibody Anti-Par-6a antibody Anti-Par6c antibody Anti-Tax Interaction Protein 40 antibody Anti-Tip-40 antibody Anti-PARD6A PAR6A antibody
Protein name	Partitioning Defective 6 Homolog Alpha Par-6 Par-6 Alpha Par-6a Par6c Tax Interaction Protein 40 Tip-40
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PAR6A_HUMAN

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