Anti-ADAM11 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O75078

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

ADAM11

Rabbit polyclonal against ADAM11

Membrane
Single-Pass Type I Membrane Protein

WB 1:500-1:2000

Disintegrin And Metalloproteinase Domain-Containing Protein 11
Adam 11
Metalloproteinase-Like-Disintegrin-Like-And Cysteine-Rich Protein
Mdc

ADA11_HUMAN