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Anti-IGF2BP3 antibody

Anti-IGF2BP3 antibody

ArtNr	STJ116296-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Immunoprecipitation Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IP
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Insulin-Like Growth Factor 2 Mrna-Binding Protein 3 antibody</br>Anti-Igf2 Mrna-Binding Protein 3 antibody</br>Anti-Imp-3 antibody</br>Anti-Igf-Ii Mrna-Binding Protein 3 antibody</br>Anti-Kh Domain-Containing Protein Overexpressed In Cancer antibody<
Similar products	Anti-Insulin-Like Growth Factor 2 Mrna-Binding Protein 3 antibody Anti-Igf2 Mrna-Binding Protein 3 antibody Anti-Imp-3 antibody Anti-Igf-Ii Mrna-Binding Protein 3 antibody Anti-Kh Domain-Containing Protein Overexpressed In Cancer antibody<
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	O00425
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Gene ID	10643
Gene symbol	IGF2BP3
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 300-579 of human IGF2BP3 (NP_006538. 2).
Short Description	Rabbit polyclonal against IGF2BP3
Tissue specificity	Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.
Cellular localization	Nucleus Cytoplasm Found In Lamellipodia Of The Leading Edge In The Perinuclear Region And Beneath The Plasma Membrane The Subcytoplasmic Localization Is Cell Specific And Regulated By Cell Contact And Growth Localized At The Connecting Piece And The Tail Of The Spermatozoa Colocalized With Cd44 Mrna In Rnp Granules In Response To Cellular Stress Such As Oxidative Stress Recruited To Stress Granules
Molecular weight	Calculated: 21kDa/63kDa. Observed: 70kDa
Dilution range	WB 1:500-1:1000 IP 1:20-1:50
Alternative names	Anti-Insulin-Like Growth Factor 2 Mrna-Binding Protein 3 antibody Anti-Igf2 Mrna-Binding Protein 3 antibody Anti-Imp-3 antibody Anti-Igf-Ii Mrna-Binding Protein 3 antibody Anti-Kh Domain-Containing Protein Overexpressed In Cancer antibody Anti-Hkoc antibody Anti-Vickz Family Member 3 antibody Anti-IGF2BP3 IMP3 KOC1 VICKZ3 antibody
Protein name	Insulin-Like Growth Factor 2 Mrna-Binding Protein 3 Igf2 Mrna-Binding Protein 3 Imp-3 Igf-Ii Mrna-Binding Protein 3 Kh Domain-Containing Protein Overexpressed In Cancer Hkoc Vickz Family Member 3
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	IF2B3_HUMAN

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Menge: 50ul

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Lieferung vsl. bis 27.09.2024

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