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Anti-AKAP5 antibody

Anti-AKAP5 antibody

ArtNr	STJ116026-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-A-Kinase Anchor Protein 5 antibody</br>Anti-Akap-5 antibody</br>Anti-A-Kinase Anchor Protein 79 Kda antibody</br>Anti-Akap 79 antibody</br>Anti-H21 antibody</br>Anti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein an
Similar products	Anti-A-Kinase Anchor Protein 5 antibody Anti-Akap-5 antibody Anti-A-Kinase Anchor Protein 79 Kda antibody Anti-Akap 79 antibody Anti-H21 antibody Anti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein an
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P24588
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
Gene ID	9495
Gene symbol	AKAP5
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human AKAP5 (NP_004848. 3).
Short Description	Rabbit polyclonal against AKAP5
Tissue specificity	Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.
Cellular localization	Membrane Lipid-Anchor Associates With Lipid Rafts
Molecular weight	Calculated: 47kDa. Observed: 47kDa
Dilution range	WB 1:500-1:2000 IF 1:50-1:200
Alternative names	Anti-A-Kinase Anchor Protein 5 antibody Anti-Akap-5 antibody Anti-A-Kinase Anchor Protein 79 Kda antibody Anti-Akap 79 antibody Anti-H21 antibody Anti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein antibody Anti-AKAP5 AKAP79 antibody
Protein name	A-Kinase Anchor Protein 5 Akap-5 A-Kinase Anchor Protein 79 Kda Akap 79 H21 Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	AKAP5_HUMAN

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