ArtNr |
STJ115502-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Regulator Of Nonsense Transcripts 1 antibody</br>Anti-Atp-Dependent Helicase Rent1 antibody</br>Anti-Nonsense Mrna Reducing Factor 1 antibody</br>Anti-Norf1 antibody</br>Anti-Up-Frameshift Suppressor 1 Homolog antibody</br>Anti-Hupf1 antibody</br>Ant |
Similar products |
Anti-Regulator Of Nonsense Transcripts 1 antibodyAnti-Atp-Dependent Helicase Rent1 antibodyAnti-Nonsense Mrna Reducing Factor 1 antibodyAnti-Norf1 antibodyAnti-Up-Frameshift Suppressor 1 Homolog antibodyAnti-Hupf1 antibodyAnt |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q92900 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthetic peptide of human UPF1 |
Short Description |
Rabbit polyclonal against UPF1 |
Tissue specificity |
Ubiquitous. |
Cellular localization |
CytoplasmP-BodyNucleusHyperphosphorylated Form Is Targeted To The P-BodyWhile Unphosphorylated Protein Is Distributed Throughout The CytoplasmLocalized In The Chromatoid Bodies Of Round Spermatids |
Molecular weight |
Calculated: 123kDa/124kDa. Observed: 135kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Regulator Of Nonsense Transcripts 1 antibodyAnti-Atp-Dependent Helicase Rent1 antibodyAnti-Nonsense Mrna Reducing Factor 1 antibodyAnti-Norf1 antibodyAnti-Up-Frameshift Suppressor 1 Homolog antibodyAnti-Hupf1 antibodyAnti-UPF1 KIAA0221 RENT1 antibody |
Protein name |
Regulator Of Nonsense Transcripts 1Atp-Dependent Helicase Rent1Nonsense Mrna Reducing Factor 1Norf1Up-Frameshift Suppressor 1 HomologHupf1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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