ArtNr |
STJ114917-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Acetylcholine Receptor Subunit Delta antibody</br>Anti-CHRND ACHRD antibody |
Similar products |
Anti-Acetylcholine Receptor Subunit Delta antibodyAnti-CHRND ACHRD antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q07001 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742. 1). |
Short Description |
Rabbit polyclonal against CHRND |
Cellular localization |
Cell JunctionSynapsePostsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Molecular weight |
Calculated: 57kDa/58kDa. Observed: 59kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Acetylcholine Receptor Subunit Delta antibodyAnti-CHRND ACHRD antibody |
Protein name |
Acetylcholine Receptor Subunit Delta |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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