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Anti-LEF1 antibody Europäischer Partner

ArtNr STJ114908-100
Hersteller St John's Laboratory
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human, Mouse
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Lymphoid Enhancer-Binding Factor 1 antibody</br>Anti-Lef-1 antibody</br>Anti-T Cell-Specific Transcription Factor 1-Alpha antibody</br>Anti-Tcf1-Alpha antibody</br>Anti-LEF1 antibody
Similar products Anti-Lymphoid Enhancer-Binding Factor 1 antibody
Anti-Lef-1 antibody
Anti-T Cell-Specific Transcription Factor 1-Alpha antibody
Anti-Tcf1-Alpha antibody
Anti-LEF1 antibody
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
Q9UJU2
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-399 of human LEF1 (NP_057353. 1).
Short Description
Rabbit polyclonal against LEF1
Tissue specificity
Detected in thymus. Not detected in normal colon, but highly expressed in colon cancer biopsies and colon cancer cell lines. Expressed in several pancreatic tumors and weakly expressed in normal pancreatic tissue. Isoforms 1 and 5 are detected in several pancreatic cell lines.
Cellular localization
Nucleus
Found In Nuclear Bodies Upon Piasg Binding
Molecular weight
Calculated: 23kDa/31kDa/34kDa/35kDa/41kDa/42kDa/44kDa. Observed: 40kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Lymphoid Enhancer-Binding Factor 1 antibody
Anti-Lef-1 antibody
Anti-T Cell-Specific Transcription Factor 1-Alpha antibody
Anti-Tcf1-Alpha antibody
Anti-LEF1 antibody
Protein name
Lymphoid Enhancer-Binding Factor 1
Lef-1
T Cell-Specific Transcription Factor 1-Alpha
Tcf1-Alpha
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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