ArtNr |
STJ114417-50 |
Hersteller |
St John's Laboratory
|
Menge |
50 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Far Upstream Element-Binding Protein 1 antibody</br>Anti-Fbp antibody</br>Anti-Fuse-Binding Protein 1 antibody</br>Anti-Dna Helicase V antibody</br>Anti-Hdh V antibody</br>Anti-FUBP1 antibody |
Similar products |
Anti-Far Upstream Element-Binding Protein 1 antibodyAnti-Fbp antibodyAnti-Fuse-Binding Protein 1 antibodyAnti-Dna Helicase V antibodyAnti-Hdh V antibodyAnti-FUBP1 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q96AE4 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 302-644 of human FUBP1 (NP_003893. 2). |
Short Description |
Rabbit polyclonal against FUBP1 |
Cellular localization |
Nucleus |
Molecular weight |
Calculated: 67kDa/68kDa. Observed: 74kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Far Upstream Element-Binding Protein 1 antibodyAnti-Fbp antibodyAnti-Fuse-Binding Protein 1 antibodyAnti-Dna Helicase V antibodyAnti-Hdh V antibodyAnti-FUBP1 antibody |
Protein name |
Far Upstream Element-Binding Protein 1FbpFuse-Binding Protein 1Dna Helicase VHdh V |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.