ArtNr |
STJ114413-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1 antibody</br>Anti-Bfa-Resistant Gef 1 antibody</br>Anti-GBF1 KIAA0248 antibody |
Similar products |
Anti-Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1 antibodyAnti-Bfa-Resistant Gef 1 antibodyAnti-GBF1 KIAA0248 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q92538 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human GBF1 (NP_004184. 1). |
Short Description |
Rabbit polyclonal against GBF1 |
Tissue specificity |
Ubiquitous. |
Cellular localization |
Golgi ApparatusCis-Golgi NetworkEndoplasmic Reticulum-Golgi Intermediate CompartmentTrans-Golgi NetworkCytoplasmLipid DropletMembranePeripheral Membrane ProteinCycles Rapidly On And Off Early Golgi MembranesStabilized On Membranes When Complexed With Arf1-Gdp And Is Released From Both Arf1 And Membranes After It Catalyzes Gdp Displacement And Arf1 Binds GtpContinuous Cycles Of Recruitment And Dissociation Of Gbf1 To Membranes Are Required For Sustained Arf Activation And Cop I RecruitmentIn Neutrophils Is Translocated From The Golgi To The Leading Edge Upon Gpcr StimulationLocalization To Lipid Droplets Is Questionable |
Molecular weight |
Calculated: 206kDa. Observed: 260kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1 antibodyAnti-Bfa-Resistant Gef 1 antibodyAnti-GBF1 KIAA0248 antibody |
Protein name |
Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1Bfa-Resistant Gef 1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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