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Anti-PPP1CA antibody

Anti-PPP1CA antibody

ArtNr	STJ114342-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Senescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Serine/Threonine-Protein Phosphatase Pp1-Alpha Catalytic Subunit antibody</br>Anti-Pp-1a antibody</br>Anti-PPP1CA PPP1A antibody
Similar products	Anti-Serine/Threonine-Protein Phosphatase Pp1-Alpha Catalytic Subunit antibody Anti-Pp-1a antibody Anti-PPP1CA PPP1A antibody
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P62136
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID	5499
Gene symbol	PPP1CA
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human PPP1CA (NP_002699. 1).
Short Description	Rabbit polyclonal against PPP1CA
Cellular localization	Cytoplasm Nucleus Nucleoplasm Nucleolus Primarily Nuclear And Largely Excluded From The Nucleolus Highly Mobile In Cells And Can Be Relocalized Through Interaction With Targeting Subunits Nom1 Plays A Role In Targeting This Protein To The Nucleolus In The Presence Of Ppp1r8 Relocalizes From The Nucleus To Nuclear Speckles Shuttles Toward The Cytosol During Infection With Veev
Molecular weight	Calculated: 32kDa/37kDa/38kDa. Observed: 38kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:200
Alternative names	Anti-Serine/Threonine-Protein Phosphatase Pp1-Alpha Catalytic Subunit antibody Anti-Pp-1a antibody Anti-PPP1CA PPP1A antibody
Protein name	Serine/Threonine-Protein Phosphatase Pp1-Alpha Catalytic Subunit Pp-1a
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PP1A_HUMAN

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Menge: 50ul

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