Anti-TIMM8A antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O60220

This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

TIMM8A

Rabbit polyclonal against TIMM8A

Mitochondrion Inner Membrane
Peripheral Membrane Protein
Intermembrane Side

WB 1:500-1:2000

Mitochondrial Import Inner Membrane Translocase Subunit Tim8 A
Deafness Dystonia Protein 1
X-Linked Deafness Dystonia Protein

TIM8A_HUMAN